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PATHWAY - A Configurable and Expandable Advanced
Thermal Stimulator for today’s & tomorrow’s research protocols,
pharmacologic investigations and clinical applications.
Contact-Heat Evoked Potential
Stimulation (CHEPS)
PATHWAY enables pain and non-painful evoked potential recording of both
A-delta & C-fiber function; allowing for the first time, selective
activation & objective identification of nerve fiber activity through
EEG recording. Extremely fast heating (70°C/Sec) and temperature
sampling (150 times/second) delivers thermal stimuli from a baseline to
55°C in 250 milliseconds with precise temperature and pattern control. |
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Windup
Superior temperature control capabilities for rapid and programmable
delivery of sensory stimuli at a windup frequency (<0.33 Hz) in
producing temporal pain summation.
"... an important modality for functional
evaluation of central pain processing mechanisms related to central
sensitizatio"
Advanced Thermal Stimulator (ATS)
ATS enables QST (Quantitative Sensory Testing) via delivery of painful
and non-painful thermal stimuli. ATS thermal stimulation can range from
-10°C to 54°C, thus opening new research horizons for deep cold pain &
heat pain studies. |
Windup Protocol
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for large review |
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fMRI
PATHWAY is available in an fMRI compatible configuration in both ATS and
CHEPS models. Rapid CHEPS stimulation can provide synchronized brain
image & fMRI compatible EEG recording of A-delta & C-fiber
electrophysiology.Software
Development Kit (SDK)
PATHWAY offers the option of a specially designed S/W program which can
be integrated with popular research programs such as "LabView" and "MatLab",
for controlling stimulation protocols. |
Ramp & Hold
Click the image for large review
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Pharmaceutical Trials
PATHWAY can potentially be used as a new 'surrogate marker' assisting in
prioritization of new & existing compounds, reduction of statistical
sample, dosage definitions - all resulting in shortening time to market.
* Pending 510(k) clearance for the availability of the ATS Thermode
in the USA for the use to 0°C degrees. The ATS Thermode is available
Internationally for use to -10°C |
+ 54 11 4583-2988
15 4071-4006
